Intravenous paracetamol: Salvage and safety proposition

An Investigation of Safety and Efficacy of Intravenous Paracetamol in Pain Management Following Cardiac Surgery

Introduction: Optimum pain management immediately after surgeries can lower the possibility of pain syndrome and its following consequences. Opioids are amongst the analgesics used for postoperative pain control; however, their application can bring about several adverse effects. In this study, all the published articles regarding efficacy of Paracetamol   in post-cardiac surgery pain managemen...

Intravenous Paracetamol and Patent Ductus Arteriosus Closure

Background: Standard medical treatments for patent ductus arteriosus (PDA) closure are, including indomethacin/ibuprofen and surgical ligation. Nowadays, a new strategy to close PDA is the use of paracetamol. The present study aimed to describe the use of intravenous (IV) paracetamol for PDA closure in neonates who present a contraindication to ibuprofen or ibuprofen failure with no possibility...

an investigation of safety and efficacy of intravenous paracetamol in pain management following cardiac surgery

introduction: optimum pain management immediately after surgeries can lower the possibility of pain syndrome and its following consequences. opioids are amongst the analgesics used for postoperative pain control; however, their application can bring about several adverse effects. in this study, all the published articles regarding efficacy of paracetamol   in post-cardiac surgery pain managemen...

Clinical Pharmacology of Intravenous Paracetamol in Neonates

Effective analgesia in neonates is still hampered due to the lack of data on pharmacokinetics and –dynamics of analgesics in this specific population. To a certain extent, this is even true for paracetamol. An intravenous formulation might improve prediction of concentration and consequent effect compared to enteral administration. In this review, we summarize the consecutive steps reported in ...

Title:covariates of Intravenous Paracetamol Pharmacokinetics in Adults